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“Introduction Various publications have addressed the negative consequences of impaired health, illness, and disease
for productivity loss at work. In a systematic Talazoparib mw GDC0449 review, Schultz et al. showed that different health conditions, such as impaired mental health, allergies, and arthritis, are associated with productivity loss at work (Schultz and Edington 2007). Likewise, individual studies have shown that the prevalence of productivity loss at work had a broad range varying between 7 and 60% among workers with impaired health (Goetzel et al. 2004; Lötters et al. 2005;
Y-27632 2HCl Meerding et al. 2005; Geuskens et al. 2008; Martimo et al. 2009). The average productivity loss at work ranged between some 12 and 34%, which accounts for 1.0 to 2.7 h per day for an 8 h workday (Goetzel et al. 2004; Lötters et al. 2005; Meerding et al. 2005; Martimo et al. 2009). A recent study also showed that a decreased ability to cope with work due to the health problems and consequent functional limitations was associated with higher productivity loss at work (Alavinia et al. 2009). Besides health-related productivity loss, a reasonable proportion of productivity loss at work will occur due to non-health-related causes, for example machine breakdown, quality problems, and logistic problems (Schultz and Edington 2007; van den Heuvel et al. 2007). Also different work characteristics, such as high physical work demands or high psychosocial work demands, may be related to productivity loss at work. For example, Alavinia et al. (2009) showed that lack of job control, adjusted for the presence of health problems with functional limitations, was associated with productivity loss at work (OR 1.36, 1.14–1.63). Among younger workers with upper extremity symptoms, a combination of high physical load as well as high job strain was also associated with productivity loss at work (Martimo et al. 2009).