GmbH, Austria) For generation of sample flow

GmbH, Austria). For generation of sample flow click here a membrane pump (Vacuubrand, Wertheim, Germany) was placed at the end of sampling system. Additional information (e.g. composition of sorption tubes, thermal desorption GC-MS settings) is provided elsewhere [61–64]. Statistical analysis Statistical

significance was calculated by the Kruskal-Wallis test, which is a non-parametric test to compare samples from two or more groups of independent observations [65]. P-values <0.05 were considered to be significant. This test was selected because it does not require the groups to be normally distributed and is more stable to outliers. To summarize the data, results are plotted as median values with 5, 25, 75 and 95 percentiles. CFU counts are presented as mean values ± standard deviation (SD). Acknowledgements The research leading to these results has received funding from the Austrian Research Promotion Agency (FFG) under project no 822696, with MS-275 industrial support from Roche Diagnostics Graz GmbH. We thank Dr. Horst Rüther for initiating this project and for his continuous input and support. A.A. greatly appreciates the generous support of the government of Vorarlberg and its governor Landeshauptmann Dr. Herbert Sausgruber. The study was supported by the Austrian Science Fund, project L313-B13 (M.N.). References 1. Madigan TM, Martinko JM,

Dunlap PV, Clark DP: Brock Biology of Microorganisms. 12th edition. Pearson 3-deazaneplanocin A Education Inc., San Francisco; 2009. 2. Goering R, Dockrell H, Zuckermann M, Wakelin D, Roitt I, Mims C, Chiodini P (Eds): Mims’ Medical Microbiology. Elsevier, Philadelphia; 2008. 3. Gibson RL, Burns JL, Ramsey BW: Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 2003,168(8):918–951.PubMedCrossRef 4. Bercault N, Boulain T: Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: a prospective case–control study. Crit Care Med 2001,29(12):2303–2309.PubMedCrossRef 5. Koulenti D, Lisboa T, Brun-Buisson C, Krueger W, Macor A, Sole-Violan Hydroxychloroquine J, Diaz E, Topeli

A, DeWaele J, Carneiro A, et al.: Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units. Crit Care Med 2009,37(8):2360–2368.PubMedCrossRef 6. Zechman JM, Aldinger S, Labows JN: Characterization of pathogenic bacteria by automated headspace concentration-gas chromatography. J Chromatogr 1986, 377:49–57.PubMedCrossRef 7. Scholler C, Molin S, Wilkins K: Volatile metabolites from some gram-negative bacteria. Chemosphere 1997,35(7):1487–1495.PubMedCrossRef 8. Eriksson A, Persson Waller K, Svennersten Sjaunja K, Haugen JE, Lundby F, Lind O: Detection of mastitic milk using a gas-sensor array system (electronic nose). Int Dairy J 2005, 15:1193–1201.CrossRef 9.

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