Setting: Research laboratory. Participants: A group of

older adults (N=39; mean age, 74.15 +/- 6.99y) with a history of falling. Interventions: Three different exercise interventions (Tai Chi, standard balance training, yoga) were given for 12 weeks. Main Outcome Measures: Balance perforniance was examined during pre- and posttest using field tests, including the 8-foot up-and-go test, 1-leg stance, functional reach, and usual and maximal walking speed. The static and dynamic balances were also assessed by postural sway and dynamic posturography, TGF-beta inhibitor respectively. Results: Training produced significant improvements in all field tests (P smaller than .005), but group difference and time x group interaction were not detected. For postural sway, significant decreases in the area of the center of pressure with eyes open (P =.001) and eyes closed (P =.002) were detected after training. For eyes open, maximum medial-lateral velocity significantly decreased for the sample (P =.013). For eyes closed, medial-lateral displacement decreased for Tai Chi (P smaller than 01). For dynamic posturography,

significant improvements in overall score (P=.001), time on the test (P=.006), and 2 linear measures in lateral (P=.001) and anterior-posterior (P smaller than 001) directions were seen for the sample. Conclusions: Yoga was as effective as Tai Chi and standard balance training for improving postural stability Citarinostat price and may offer an alternative to more traditional programs. (c) 2014 by the American Congress of Rehabilitation Medicine”
“Background: Evidence from experimental and epidemiologic studies suggests that vitamin B6 may reduce the risk

of breast cancer.\n\nMethods: We examined the association of prediagnostic plasma concentrations Smoothened Agonist of pyridoxal-5′-phosphate (PLP), an active form of vitamin B6, with postmenopausal breast cancer risk in a case control study nested in the multiethnic cohort in Hawaii and Southern California, including 706 cases and 706 controls matched on date of birth, ethnicity, study site, date of blood draw, time of blood draw, hours of fasting before blood draw, and use of menopausal hormones. OR and 95% confidence intervals (Cl) were calculated using conditional logistic regression models.\n\nResults: Women with plasma PLP concentrations in the highest quartile had a 30% reduced risk of invasive breast cancer (CI: 0.50-0.98) as compared with the women in the lowest PLP quartile (P for trend = 0.02). The association seemed to be limited in cases with hormone receptor-positive tumors (P for heterogeneity = 0.04); and remained unchanged in the analysis restricted to women with blood samples collected more than one year before cancer diagnosis (OR = 0.69; CI: 0.48-0.99; P for trend = 0.03).\n\nConclusions: These data suggest that higher circulating levels of vitamin B6 are associated with a reduced risk of invasive postmenopausal breast cancer.