The computer software program includes GUI, temperature conversion, as well as three modules for the localization algorithm; the localization algorithm running on the computer, the location information and temperature data is displayed in the GUI.Figure 2.The system program structure.3.?RFID Temperature Sensor Tag Design3.1. The Temperature Sensor ChipAs in this paper the SL900A [25] chip is used as the core component of the body-temperature monitoring and data transmission part of the experimental system, we show the structure of this temperature-sensor chip in Figure 3. The SL900A single-chip RFID data-logger is a smart semi-active tag with a transponder integrated circuit (IC) that combines a temperature sensor and can automatically both track and record the temperature as well as take readings from an external sensor.

The integrated temperature sensor has a typical nonlinearity of ��0.5 ��C over the specified temperature range. The device has a real time clock (RTC) and can be configured to notify users automatically in case of an event. It operates in both semi-passive (battery-assisted) o
Over the past few decades, many of the advances in real-time, integrated chemical and biological sensing have been enabled by improvements in fabrication methods or by the increase in computational power for predictive modeling of device performance [1,2]. For example, the ability to create dense arrays of integrated silicon nanowire sensors required the development of nanofabrication techniques and device packaging methods [3].

Although these capabilities were originally motivated by the need for smaller integrated electronic circuits for computers and other electronic devices, they have been leveraged to enable other fields, particularly sensors research. Additionally, advances in computing power have enabled real-time detection and analysis of increasingly complex data signals.Because integrated sensors can be fabricated in numerous formats, they have impacted nearly every aspect of society, from the automotive industry and defense to healthcare and drug development [4]. As such, the complexity Dacomitinib of sensor design varies greatly, from the simple carbon monoxide detector to the gyroscope. However, in all cases, quickly obtaining a reliable and robust signal is critical.1.1. Labeled vs. Label-Free SensorsThe present review is focused on label-free detection methods.

In contrast to labeled detection, which requires a secondary molecule or amplification step, label-free detection allows the sensors to directly detect the molecule of interest. For example, a labeled detection method (Figure 1a) captures the analyte of interest using primary antibodies, and indirectly detects the bound analyte using fluorescently labeled secondary antibodies. In contrast, a label-free sensor (Figure 1b) is able to directly sense when the protein binds to the antibody.