2 ± 0 5 vs 17 6 ± 0 4; P = 0 4582) The maximum Borg value was n

2 ± 0.5 vs. 17.6 ± 0.4; P = 0.4582). The maximum Borg value was not see more Different between groups (Table 2), because all the participants reached exhaustion before finishing the test. Seven-day food records before the exercise test revealed no significant group differences in energy or macronutrient intake. Energy intake was 2195 ± 527 Kcal, containing PF-01367338 research buy 247 ± 66 g of carbohydrate, 88.4 ± 24.1 g of fat and 100 ± 25 g of protein for all

subject combined. Similarly, no changes in food intake were recorded thorough the study period. To avoid the influence of possible changes in plasma volume caused by exercise, CBC was adjusted following the methodology proposed by Dill and Costill [31]. There was a significant effect of time during MK-1775 in vitro the exercise test (basal, 30 min, 150 min) for total leukocyte, neutrophil an lymphocyte counts (P < 0.05) (Table 3), namely an increase in total leukocyte and neutrophil counts at 150 min after exercise and a decrease in lymphocyte counts 30 and 150 min after exercise. However no differences between groups or across exercise tests (day 0 and day 30) were detected in the pattern of response except for the lymphocyte counts. Thus on day 30 the I group, supplemented with nucleotides, did experience a decrease in lymphocyte counts at 30 min compared to the basal values but a total recovery was registered at 150 min,

while the placebo group stayed low and was significantly reduced compared with the I group (P = 0.0028). Table 3 Blood count during N-acetylglucosamine-1-phosphate transferase exercise tests before and after 30 days of supplementation Variable Day 0 Inmunactive Placebo Day 30 Inmunactive Placebo Total leukocytes (109 · L-1)         Basal 6.38 ± 0.53b 6.10 ± 0.47b 7.00 ± 0.71b 5.25 ± 0.44b 30 min 6.34 ± 0.76b 6.72 ± 0.93b 6.83 ± 0.74b 5.66 ± 0.72b 150 min 10.45 ± 1.19a 9.86 ± 1.03a 10.36 ± 0.86a 8.32 ± 0.96ª Neutrophils (109 · L-1)         Basal 3.69 ± 0.35c 3.27 ± 0.41b 4.06 ± 0.43b 2.98 ± 0.38b 30 min 4.30 ± 0.70b 4.65 ± 0.87b 4.30 ± 0.54b 3.83 ± 0.70b 150 min 8.06 ± 0.89a 7.80 ± 1.01a 7.27 ± 0.59a 7.17 ± 1.05ª Lymphocytes (109 · L-1)         Basal 2.03 ± 0.14ª 2.03 ± 0.13ª 2.12 ± 0.22ª 1.73 ± 0.12ª 30 min 1.37 ± 0.09b 1.39 ± 0.12b 1.77 ± 0.17b

1.44 ± 0.09b 150 min 1.68 ± 0.11b 1.43 ± 0.11b 2.27 ± 0.37ª* 1.50 ± 0.07ab Values are means ± SE (n = 10). Different superscripts indicate significant differences across time within a group treatment. An asterisk indicates significant differences between groups at specified time point (P < 0.05). There was no effect of time (basal or 150 min), exercise test (day 0 or day 30) or treatment group on salivary IgA concentration (P > 0.05) (Table 4). Similarly, there was no significant effect of exercise on the lymphoproliferative response, although an almost significant decrease was observed in the I group at baseline, i.e.

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